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RelistaseTM is a new tetrapeptide from Lipotec created for skin elasticity and tightness enhancement in cosmetic formulations.  Identified by a combinatorial chemistry approach from a library of more then 330,000 peptides, the library was screened to evaluate the inhibitory potency of the various peptides on the activity of elastase enzyme. Through this process, the peptide in RelistaseTM was found to best inhibit excess elastase activity, helping to improve skin elasticity lost due to the normal process of aging or by extransic factors such as excessive solar exposure or air pollution among others. 

By reducing excess elastase activity, RelistaseTM helps to protect elastin and other ECM components which are susceptible to degradation by these enzymes resulting in loose, sagging and wrinkled skin. The tetrapeptide also exhibits collagen boosting properties favoring connective tissue improvement, enhancing tensile strength and elastic resistance, thus leading to firmer, tighter, elastic and younger skin.

Cosmetic  Properties

  • A molecular cosmetic active peptide that enhances  skin's elasticity and tightness especially targeted for mature skin
  • Helps to protect elastin by inhibiting human neutrophil elastase activity
  • Improves tightness and overall skin elasticity as proven in vivo
  • Collagen boosting properties help with connective tissue improvement and restoration of the skin's three-dimensional integrity, as proven in vitro

Incorporation: At the final stage of the manufacturing process, cool down, provided the temperature is no higher than 104 to 113°F (40-45°C). The pH of the final formulation should range between 5.0 to 7.0.

Recommended Usage Rate: 4%
Appearance: Colorless translucent solution
Solubility: Water soluble
Long Term Storage:  Cool, clean and dark place. If kept in these conditions shelf life is at least 18 months.

INCI: Glycerin (and) Acetylarginyltryptophyl Diphenylglycine

Do not directly apply onto your skin. This product should be added to a formulation at the recommended usage rate.

Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.

Here you will find Material Safety Data Sheets (MSDS) and Technical Data Sheets. The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.


Technical Data
Relistase Technical Data
Material Safety Data Sheet (MSDS)

Relistase MSDS

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