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Leucidal Liquid

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Leucidal Liquid
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LeucidalŽ Liquid - Approved for use in ECOCert Certified Organic products

LeucidalŽ Liquid is a new, natural preservative from Active Micro Technologies combining the current trends for alternative preservative systems and peptide technology. Derived from radishes fermented with Leuconostoc kimchii, a lactic acid bacteria that has traditionally been used to make kimchi, this product consists of an isolated peptide that is secreted from the bacteria during the fermentation process that has been shown to have antimicrobial benefits. LeucidalŽ Liquid is accepted by ECOCERT as an ingredient in certified organic cosmetics.

As with all biological materials some attention must be paid to the conditions under which LeucidalŽ Liquid can be used. Preliminary investigation shows that the material is stable with regard to temperature up to 60°C (140°F). Testing shows that the peptide remains active under both acidic and basic conditions, but there is a loss of activity at pH of 9.

For many cosmetic formulations LeucidalŽ Liquid can function as a natural alternative to synthetic preservatives. It may also be useful as a topical antimicrobial when addressing problem skin or scalp conditions. While it has only a slight odor, it will impart some color to clear cosmetic products, although it is still possible to formulate "white" emulsions.

Challenge testing reveals that 2% Leucidal Liquid in a cream base is able to successfully inhibit microbial growth. Samples were inoculated with S. aureus, E. coli, P. aeruginosa, C. albicans, A. niger, K. pneumoniae, B. cepacia. Following 28 days of incubation samples were then re-inoculated for an additional 28 days. Minimum Inhibitory Concentrations (MIC) were determined using a standard agar dilution method. A variety of bacteria and fungus were tested to evaluate the ability of LeucidalŽ Liquid to protect against microbial contamination. The results indicate that LeucidalŽ Liquid can provide effective protection for certain cosmetic systems.

The choice of preservatives for personal care formulations should be carefully considered. This is especially true when using natural antimicrobials and or other “mild” antimicrobials. We recommend that every formula undergo stability and microbial testing to ensure adequate preservation.

Key Benefits

  • Water soluble
  • Naturally derived
  • Virtually odorless
  • Heat stable to 60°C (140°F)
  • Broad spectrum of antibacterial activity
  • Compatible with a wide range of cosmetic ingredients.
  • Very mild, with low to no irritation potential
  • ECOCert Approved for use in ECOCert Certified Organic products

Please note, Active Micro Concepts now recommends a usage rate of 2.0 - 4.0% for this preservative.

Recommended Usage Level: 2.0% - 4.0%
pH (as supplied): 4.0 - 6.0
Appearance: Clear to slightly hazy yellow to light amber liquid
Solubility: Soluble in water, glycerin and propylene glycol, immiscible with oils.
Shelf Life: 12 months
Storage and Use: Sealed container away from sunlight. Do not freeze, store at or near room temperature. Mix well prior to use; may sediment on standing.

INCI: Leuconostoc/Radish Root Ferment Filtrate

Here you will find Material Safety Data Sheets (MSDS) and Technical Data Sheets. The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.

Technical Data
Leucidal Liquid Technical Data
Material Safety Data Sheet (MSDS)

Leucidal Liquid MSDS

Lotioncrafter formulas in which this ingredient appears are listed below. Formulas are used as a means to provide basic formulating information and guidance in the use of ingredients Lotioncrafter supplies. Formulations are provided in percentages, grams and ounces. Most create a batch size of 1000g (33 ounces). Because percentages are provided, they can be sized up or down with ease.

The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.


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By accessing this formulation you acknowledge that it is your responsibility to ensure formulation integrity and freedom to practice and that the information herein is provided with no warranties express or implied. Ensuring suitability and stability is your responsibility in every respect and should include doing appropriate formula stability and preservative efficacy testing as well as appropriate patent search and analysis.

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