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CAS No. 16485-10-2

D,L-Panthenol, aka Pro-Vitamin B5, is a stable lit racemic mixture of D-Panthenol and L-Panthenol. The human body readily absorbs DL-Panthenol through the skin and it rapidly converts D-Panthenol to Pantothenic Acid (Vitamin B5), a natural constituent of healthy hair and a substance present in all living cells. Only D-Panthenol is converted to Vitamin B5 and not the L-Panthenol. So the racemic D,L-Panthenol has only half of the physiological activity of D-Panthenol in skin care.

Studies have shown D-Panthenol promotes stimulation of epithelization, granulation, mitigation of itching and has an anti-inflammatory effect.  When used in formulations over the course of three to four weeks, it has the potential to improve the appearance of the skin, including dryness, roughness, scaling, pruritus and erythema.  Further, its moisturizing properties improve stratum corneum hydration, reducing transepidermal water loss and maintaining skin elasticity and softness. Panthenol also works with DMAE in the production of acetylcholine which firms and tones the skin.

Both D-Panthenol and DL-Panthenol are equally effective for moisturization, improvement of hair structure and adding luster and sheen to the hair.  

This is a cosmetic raw material and is meant for external use only in cosmetic formulations.  As with all of our materials, it should not be taken internally.

Recommended Usage: 1-5%
Appearance: White crystalline powder
Solubility: Soluble in water
Assay: Min 99.0%
Standard: Conforms to FCC/USP Specifications
Country of Origin: China
Shipping Info: HS# 2936.24.0000

INCI: Panthenol

California Prop 65 Statement: The following statement is made in order to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. This product is not known to the State of California to cause cancer, birth defects or other reproductive harm.

Here you will find Safety Data Sheets (SDS) and Technical Data Sheets. The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.

Technical Data

Safety Data Sheet (SDS)
dl-Panthenol SDS


Lotioncrafter formulas in which this ingredient appears are listed below. Formulas are used as a means to provide basic formulating information and guidance in the use of ingredients Lotioncrafter supplies. Formulations are provided in percentages, grams and ounces. Most create a batch size of 1000g (33 ounces). Because percentages are provided, they can be sized up or down with ease.

The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.

DIY C&E with Ferulic Acid
DIY Hydrating B5 Gel
Exfoliating Body Conditioner
Hydrating & Conditioning Gel Serum
Hydrating Resveratrol & Niacinamide Facial Moisturizer
Moisturizing Lotion with Simulgreen™ 18-2.pdf
Simple & Luxurious Hair Conditioner
Soothing & Clarifying Serum
Soothing & Moisturizing Lotion with Montanov 68
Time DefyTM Facial Serum

By accessing this formulation you acknowledge that it is your responsibility to ensure formulation integrity and freedom to practice and that the information herein is provided with no warranties express or implied. Ensuring suitability and stability is your responsibility in every respect and should include doing appropriate formula stability and preservative efficacy testing as well as appropriate patent search and analysis.

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