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Decorinyl™




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Decorinyl™
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DECORINYL™
CAS: Mixture

Decorinyl™ is a synthesized tetrapeptide which mimics the sequences of decorin that bind to collagen fibrils. It has been shown to regulate fibrillogenesis and control fibril growth, improving firmness and elasticity of the skin, ensuring uniformity of fibril diameter and spacing of collagen fibrils. In effect, it replaces the non-functional decorin encountered as the skin ages, and also sustains a superior moisture profile.

Fibrillogenesis is an essential process in tissue formation, but must be controlled and regulated in order to avoid excessive bundle-like aggregation of collagen. The fibrillogenesis control is the role of decorin, a small leucine-rich proteoglycan, which is associated with collagen fibrils at specific binding sites in the protein core, controlling fibril dimensions, the uniformity of their diameter and their regular spacing.

Aging skin contains a truncated form of decorin, which lacks binding regions with collagen fibrils, producing a negative effect on the elasticity on the skin. Decorinyl™ is a mimic peptide of these binding sequences that has been proven to regulate fibrillogenesis, control collagen fibril diameter and increase skin suppleness.

Decorinyl™ has been incorporated into a liposomal system for enhanced penetration, stability and efficacy. It is recommended for cosmetic formulations designed for mature skin where an improvement of suppleness and strength of skin is desired. It may be used in emulsions, gels and other formulations.

Incorporation: Decorinyl™ can be incorporated in the final stage of the manufacturing process, when the temperature has cooled to at minimum of 35 - 40°C (95 - 104°F). Care should be taken not to exceed 50°C (122°F)

Appearance: Off white to amber liquid suspension
pH: 5.0 - 6.5
Tripeptide-10 Citrulline Content: 0.2%
Solubility: Water soluble
Preservative: 0.9% Phenoxyethanol
Recommended Usage Rate: 5%
Manufacturer: Lipotec
Country of Origin: Spain
Storage: Keep in a cool (between 15 and 25°C /59 and 77°F), dark and clean place. In order to avoid secondary microbial contamination, following opening, containers should be handled with special care. If stored as recommended, Decorinyl™ remains stable for at least 12 months.

INCI: Water (and) Lecithin (and) Tripeptide-10 Citrulline (and) Carbomer (and) Triethanolamine (and) Caprylyl Glycol


Do not directly apply onto your skin. This product should be added to a formulation at the recommended usage rate.

Shipping Information: HS Code 3824909160

Disclaimer
Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.

California Prop 65 Statement: The following statement is made in order to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. According to the manufacturer, this product is not known to the State of California to cause cancer, birth defects or other reproductive harm. Please see the Product Information Dossier under Technical Data for further information.

Here you will find Safety Data Sheets (SDS) and Technical Data Sheets. The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.

Technical Data
Decorinyl™ Technical Presentation
Decorinyl™ Marketing Presentation
Decorinyl™ Product Information Dossier

 

Safety Data Sheet (SDS)

Decorinyl™ SDS

 

Lotioncrafter formulas in which this ingredient appears are listed below. Formulas are used as a means to provide basic formulating information and guidance in the use of ingredients Lotioncrafter supplies. Formulations are provided in percentages, grams and ounces. Most create a batch size of 1000g (33 ounces). Because percentages are provided, they can be sized up or down with ease.

The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.

Formulations
Antiaging Facial Moisturizer for Mature Skin

By accessing this formulation you acknowledge that it is your responsibility to ensure formulation integrity and freedom to practice and that the information herein is provided with no warranties express or implied. Ensuring suitability and stability is your responsibility in every respect and should include doing appropriate formula stability and preservative efficacy testing as well as appropriate patent search and analysis.


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10-26-2018
We have been experiencing a disrupted ferry service schedule this week that will continue for another week at a minimum. The effect of this change in scheduling is that some UPS shipments may be 1 day longer to be delivered than usual. This especially affects expedited services like UPS Next Day, 2nd Day and 3 Day Select. This is a situation beyond UPS' control and they will NOT honor refunds for late delivery caused by the ferry service delays. We apologize for this inconvenience beyond our control.

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