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Cosmoperine




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Cosmoperine
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 Cosmoperine®

 Cosmoperine, also known as tetrahydropiperine (THP), is derived from piperine, the active principle of black peppercorns (Piper nigrum) which acts as a penetration enhancer when added to water soluble ingredients. It works by enhancing the bioavailability of nutrients, including vitamins, minerals, coenzymes, and nutraceutical herbal extracts. An increase in topical permeation was shown when combining Cosmoperine with products like Green Tea extract; an antioxidant rich in polyphenols, Coleus Forskohlli Extract; a skin conditioning agent and Tetrahydrocurcumin; derived from Curcuminoids as extracted from Tumeric Root, acting as a potent antioxidant. One study showed an enhanced absorbtion of 30% in Vitamin C and Beta Carotene.

While at present there is insufficient experimental data to determine the actual mechanism of THP’s bioenhancing properties, it is postulated that THP may operate by increasing either the membrane’s fluidity and/or the affinity of the nutrient to the cell membrane. THP is also a lipophilic compound and may therefore increase solubilization of the intracellular lipid moiety in the skin, making it more permeable to the applied nutrient.

Recommended Usage Rate: 0.1-1.0%

Appearance: White powder
Solubility: Soluble in Dimethyl Isosorbide (2 parts DMI to 1 part Cosmoperine), Ethoxydiglycol and ethanol, partially soluble in propylene glycol, insoluble in water and glycerin
Storage: Store in cool, dry place in original container away from light and moisture
Shelf life: Three years, properly stored.

INCI: Tetrahydropiperine

Cosmoperine® is a patented product of Sabinsa Corporation.

California Prop 65 Statement: The following statement is made in order to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. This product is not known to the State of California to cause cancer, birth defects or other reproductive harm.

Here you will find Material Safety Data Sheets (MSDS) and Technical Data Sheets. The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.

Technical Data

 
Cosmoperine as Enhancer of Nutrient and Drug Bioavailability

 

Material Safety Data Sheet (MSDS)

Cosmoperine MSDS

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News
11-20-2018
Lotioncrafter will be closed on Thursday and Friday, November 22nd and 23rd for the Thanksgiving holiday. During that time email and telephone calls will not be returned (we will respond as quickly as possible next week, after shipping deadlines have been met on Monday afternoon). Our shopping cart will remain active and we will continue to process orders. UPS and Mail shipping will resume on Monday morning, November 26th. DUE TO THE CLOSURE, IF YOU CALL OR WRITE TO ALTER ORDERS ONCE THEY ARE PLACED, DUE TO THE VOLUME OF ORDERS WE WILL BE PROCESSING MONDAY, WE CANNOT GUARANTEE WE WILL SEE YOUR EMAIL OR HEAR YOUR MESSAGE BEFORE SHIPPING. IF WE ARE ABLE TO DO SO, YOUR ORDER WILL BE PULLED FROM THE QUEUE, ADJUSTED AND SHIPPED AFTER OTHER ORDERS WHICH COULD DELAY SHIPPING BY A DAY. Thank you for your understanding. TO ALL OF OUR USA CUSTOMERS, WE WISH YOU A SAFE AND ENJOYABLE THANKSGIVING HOLIDAY!!

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