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CAS No.: Mixture

Special Notice: The current lot from the manufacture is hazy yellow instead of a clear yellow color.  Labortoires Expansience confirmed their retained is the same and advised us this is normal and within specification.  Given the low usage rate, it should not affect your formulation.  It can be heated prior to use and that should make the oil clearer.

Collageneer® is an anti-aging and firming ingredient that stimulates the synthesis of a high-quality collagen to increase elasticity and firmness in the skin, helping to remodel the facial contour.

Collageneer® is made from lupeol, which is extracted from the coatings of sweet white lupin seeds in a patented process. Once extracted, the lupeol is solubilized in oleic sunflower oil and then semi-refined and stabilized by adding natural ±-tocopherol. Sourced from lupine plants cultivated using sustainable agricultural practices in France.

Collageneer® works by stimulating the production of HSP47 in the skin. HSP47 is a collagen-specific I molecular chaperone which helps the synthesis of good quality procollagen I.


  • Increases skin firmness and elasticity
  • Remodels the facial profile
  • Anti-aging


  • Anti-aging skin care products
  • Remodeling skin care products
  • Firming skin care products
  • Eye contour treatments

In vitro tests:

In a 72-hour treatment, Lupeol increased production and secretion of type I collagen by 46%.

In a 48-hour treatment, Lupeol induces overproduction of HSP47, a type I molecular chaperone, at a rate of +21%.

In vivo tests:

25 volunteers aged 45 to 65 years tested a cream with 2% Collageneer® for 89 days.

  • Skin elasticity test via cutometer showed increases in the Ur/Ue and Ur/Uf parameters of 11.2% and 10.6 percent, respectively, at T89.
  • Facial contour was remodeled, showing a significant reduction of facial oval sag volume at T42 and T89.
  • In self-assessments, 92% of the volunteers noticed improved firmness of the skin and 72% noticed reduced sagging of the facial contour.

Formulation Guidelines:

  • Optimal temperature to add to a formulation is 104°F (40°C) or below. May be added at up to 167°F (75°C) just before blending, over a short period of time
  • Soluble in lipids.
  • When used in an emulsion, pH of final formulation should be close to 6.5.

Recommended Usage Rate: 0.5 - 2%
Appearance: Oily yellow to orange-brown liquid, may be clear or hazy, with characteristic odor
Manufacturer: Laboratoires Expanscience
Country of Origin: France
Preserved with: No preservatives. Stabilized with Alpha-Tocopherol of natural origin.
pH of ingredient: Not applicable; non-aqueous product
Long Term Storage: Store between 59°F to 77°F (15°C to 25°C), under nitrogen or other inert gas, protected from light, heat, and humidity.
Shelf Life:  18-24 months from date of purchase

INCI: Helianthus Annuus (Sunflower) Seed Oil and Lupinus Albus Seed Extract

Lotioncrafter blankets all our bottles with inert Argon gas prior to sealing them to protect the contents.  Argon is an inert heavy gas that sits on top of the oil, shielding it from oxygen.  When you open larger bottles to pour out contents, the invisible Argon gas is poured out, too.  With larger capped bottles (60ml and over), you will want to top them off again for storage using Ox-Blox.  With dropper bottles, you can angle them or turn them upside down to dispense the contents and keep the Argon gas in the bottle (clever, right?).

Shipping Info:  HS# 1515909900

Collageneer® is a registered trademark of Laboratoires Expanscience, the manufacturer.

Do not directly apply onto your skin. This product should be added to a formulation at the recommended usage rate.

Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat and cure, or prevent disease. Always consult with your professional skin care provider.


California Prop 65 Statement: The following statement is made in order to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. This product is not known to the State of California to cause cancer, birth defects or other reproductive harm.

Here you will find Safety Data Sheets (SDS) and Technical Data Sheets. The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.

Technical Data
Collageneer® Marketing Presentation
Collageneer® Product Sheet
Collageneer® Technical Data

Safety Data Sheet (SDS)
Collageneer® SDS


Lotioncrafter formulas in which this ingredient appears are listed below. Formulas are used as a means to provide basic formulating information and guidance in the use of ingredients Lotioncrafter supplies. They are not tested for efficacy, stability or preservative efficacy. Formulas are used as a means to provide basic formulating information and guidance in the use of ingredients Lotioncrafter supplies. Formulations are provided in percentages, grams and ounces. Most create a batch size of 1000g (33 ounces). Because percentages are provided, they can be sized up or down with ease.

The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.


Lupine & Date Collagen Boosting Antiaging Serum

By accessing this formulation you acknowledge that it is your responsibility to ensure formulation integrity and freedom to practice and that the information herein is provided with no warranties express or implied. Ensuring suitability and stability is your responsibility in every respect and should include doing appropriate formula stability and preservative efficacy testing as well as appropriate patent search and analysis.

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So that our staff may enjoy the Memorial Day Holiday, Lotioncrafter's offices will be closed on Monday, May 28th. We will reopen on Tuesday, May 29th. During this time, we will not be returning phone calls or email messages. Shipping will resume on Tuesday, May 29th. Orders, emails and phone calls will be handled in the order received, as best we are able. Please expect some delays as we work through the holiday backlog! We also cannot guarantee changes to orders will be seen before orders have shipped, those that we do catch, will be held back to adjust, which will mean a shipping delay. We appreciate your understanding. Have a safe and happy Memorial Day!

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