TEGO® Pep 4-Even 

TEGO® Pep 4-Even is a new peptide developed to balance skin tone. There are various mechanisms to brighten skin tone, including reducing or inhibiting tyrosinase activity, blocking melanin transfer into keratinocytes, and inhibition of melanocyte activation.  It is theorized that TEGO® Pep 4-Even works by reducing the amount of tyrosinase and inhibiting melanocyte activation.

In vivo skin lightening studies have shown TEGO® Pep 4-Even to notably reduce yellow skin tone starting at 4 weeks and fading age spots after 8 weeks. It has been shown to significantly improve the overall appearance after 2 weeks and the evenness of skin tone after 4 weeks.  Skin lesion were significantly reduced after 4 weeks of use.  According to the manufacturer, its use with Sodium Ascorbly Phosphate, a Vitamin C derivative, has been shown to improve its performance significantly. All studies were performed at a usage rate of the peptide equivalent to 2.5% TEGO® Pep 4-Even in the test formulation.

Applications

• Skin lightening preparation (e.g. hand creams)
• Anti-aging products with correction of age spots and pigmentation
• Anti-aging products for even skin tone
• Ethnic skin care
• Décolletté preparations

Benefits

• Visibly diminishes hyperchromatic spots
• Improves evenness of skin tone
• Reduces lesions and melasma on ethnic skin
• Active on all kinds of skin types
• Provides significant anti-inflammatory effect
• Skin-friendly
• Safely inhibits the pigmentation process

Formulation Guidelines

Preparation of O/W emulsion (cream or lotion): TEGO® Pep 4-Even can either be added during the cooling process at temperatures below 40°C (104°F) or directly to the water phase of the emulsion in cold-process formulations. Then the emulsion is prepared as usual.

Preparation of  W/O emulsion (cream or lotion):  TEGO® Pep 4-Even can either be added prior to the homogenization at temperatures below 30°C (86°F) or directly to the water phase in cold-process formulations. Then the W/O-emulsion is prepared as usual. 

Recommended Usage Rate: 0.5-5%, 
Appearance: Colorless clear viscous liquid
Peptide Content: 1600 ppm
Long Term Storage: Recommended at 39° - 46°F (4° - 8°C)

INCI: Tetrapeptide-30 (and) Glycerin (and) Water **

** INCI as registered is Tetrapeptide-30 and earlier marketing data may reflect an incorrect proposed INCI name of Tetrapeptide-27.

Do not directly apply onto your skin. This product should be added to a formulation at the recommended usage rate.

Disclaimer
Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.